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Smiths Detection

IONSCANTM

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The ultimate alternative to HPLC-The fastest route to cleaning validation

 

The IONSCAN detects and quantitates trace analytes using ion mobility spectrometry (IMS). A solid or liquid sample is introduced to the analyzer by thermal desorption or direct injection. The resultant vapors are swept in through the inlet by the carrier gas and ionized. The product ions are gated into the drift tube and accelerated by an electric field
toward the detector. Air flows through the drift tube in a direction counter to the electric field. Drift times depend on
the size, shape, and mass of the ionized analyte and range from about 3 to 50 milliseconds.

The characteristic speed at which an ion moves under the influence of an electric field, i.e., its ion mobility, is a distinct thumbprint that identifies the original substance.
 



Product Notes
IONSCAN-LS

Fast quantitative analysis with the IONSCAN-LS offers
the advantage of simplicity, selectivity, sensitivity,
atmospheric pressure operation, and ease of use.
These features, together with 21 CFR Part 11
compliance, make it ideal for use in pharmaceutical
cleaning validation applications and make it the
ultimate alternative to HPLC.

IONSCAN 400B

The IONSCAN-LS 400B detects and identifies over 40
explosives or narcotic substances. A simple wipe with a
swab over items such as checked or carry on luggage,
portable electronic devices, and packages is all that is
necessary to collect a sample which is then places into
the IONSCAN for analysis. The IONSCAN is ideal for
aviation security needs. 

                                        
 

The IonScan-LS
Product Note

The IonScan 400B    Product Note
Reference Corner
 

 Published Articles

1. IMS for Drug Making

2. Novel Analytical Approaches to Solving
Pharmacutical Problems

3. Ion Mobility Spectrometry for Determination
of Active Drugs in Blinded Dosage Forms

4. IONSCAN-LS IMS - Fast, Efficient Cleaning Validation

5. IMS for Cleaning Verification

 

Demonstration Video

Application Notes


1. IMS Detection of Dober Detergent - Chematic 91 AE

2. IMS Detection of Dober Detergent - Chematic 82 AE

3. Detection of Chematic 99 AE Detergent

4. Detection of Formula 939 Detergent

5. Detection of ND - 165 Detergent

6. Detection of Chematic 91 Detergent

7. IMS for Detection and Quantification of Active Pharmaceutical ingredients for Personal Air Monitoring

8. Personal Air Monitoring Detection & Qualification


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